Publikationen von Nicole Paczia

Zheng, L.; Li, W.; Christ, M.; Paczia, N.; Buckel, W.; Mais, C.-N.; Bolker, M.; Freitag, J.; Bange, G.: Mechanistic and structural insights into the itaconate-producing trans-aconitate decarboxylase Tad1. PNAS Nexus 4 (3), pgaf059 (2025)

Orsi, E.; Schulz-Mirbach, H.; Cotton, C. A. R.; Satanowski, A.; Petri, H. M.; Arnold, S. L.; Grabarczyk, N.; Verbakel, R.; Jensen, K. S.; Donati, S. et al.; Paczia, N.; Glatter, T.; Küffner, A. M.; Chotel, T.; Schillmüller, F.; De Maria, A.; He, H.; Lindner, S. N.; Noor, E.; Bar-Even, A.; Erb, T. J.; Nikel, P. I.: Computation-aided designs enable developing auxotrophic metabolic sensors for wide-range glyoxylate and glycolate detection. Nature Communications 16 (1), 2168 (2025)

Schulz-Mirbach, H.; Wichmann, P.; Satanowski, A.; Meusel, H.; Wu, T.; Nattermann, M.; Burgener, S.; Paczia, N.; Bar-Even, A.; Erb, T. J.: New-to-nature CO₂-dependent acetyl-CoA assimilation enabled by an engineered B12-dependent acyl-CoA mutase. Nature Communications 15, 10235 (2024)

Lago-Maciel, A.; Soares, J. C.; Zarzycki, J.; Buchanan, C. J.; Reif-Trauttmansdorff, T.; Schmidt, F. V.; Lometto, S.; Paczia, N.; Schuller, J. M.; Hansen, D. F. et al.; Heller, G. T.; Prinz, S.; Hochberg, G. K. A.; Pierik, A. J.; Rebelein, J. G.: Methylthio-alkane reductases use nitrogenase metalloclusters for carbon-sulfur bond cleavage. bioRxiv: the preprint server for biology, 2024.10.19.619033 (2024)

He, H.; Gómez-Coronado, P. A.; Zarzycki, J.; Barthel, S.; Kahnt, J.; Claus, P.; Klein, M.; Klose, M.; de Crécy-Lagard, V.; Schindler, D. et al.; Paczia, N.; Glatter, T.; Erb, T. J.: Adaptive laboratory evolution recruits the promiscuity of succinate semialdehyde dehydrogenase to repair different metabolic deficiencies. Nature Communications 15 (1), 8898 (2024)

Barthel, S.; Brenker, L.; Diehl, C.; Bohra, N.; Giaveri, S.; Paczia, N.; Erb, T. J.: in vitro transcription-based biosensing of glycolate for prototyping of a complex enzyme cascade. Synthetic Biology, ysae013 (2024)

Pozhydaieva, N.; Billau, F. A.; Wolfram-Schauerte, M.; Ramírez Rojas, A. A.; Paczia, N.; Schindler, D.; Höfer, K.: Temporal epigenome modulation enables efficient bacteriophage engineering and functional analysis of phage DNA modifications. PLOS Genetics 20 (9), e1011384 (2024)

Scarinci, G.; Ariens, J.-L.; Angelidou, G.; Schmidt, S.; Glatter, T.; Paczia, N.; Sourjik, V.: Enhanced metabolic entanglement emerges during the evolution of an interkingdom microbial community. Nature Communications 15 (1), 7238 (2024)

Arias-Rojas, A.; Arifah, A. Q.; Angelidou, G.; Alshaar, B.; Schombel, U.; Forest, E.; Frahm, D.; Brinkmann, V.; Paczia, N.; Beisel, C. L. et al.; Gisch, N.; Iatsenko, I.: MprF-mediated immune evasion is necessary for Lactiplantibacillus plantarum resilience in the Drosophila gut during inflammation. PLOS Pathogens 20 (8), e1012462 (2024)

Schulz-Mirbach, H.; Krüsemann, J. L.; Andreadaki, T.; Nerlich, J. N.; Mavrothalassiti, E.; Boecker, S.; Schneider, P.; Weresow, M.; Abdelwahab, O.; Paczia, N. et al.; Dronsella, B.; Erb, T. J.; Bar-Even, A.; Klamt, S.; Lindner, S. N.: Engineering new-to-nature biochemical conversions by combining fermentative metabolism with respiratory modules. Nature Communications 15 (1), 6725 (2024)

Schann, K.; Bakker, J.; Boinot, M.; Kuschel, P.; He, H.; Nattermann, M.; Paczia, N.; Erb, T. J.; Bar-Even, A.; Wenk, S.: Design, construction and optimization of formaldehyde growth biosensors with broad application in biotechnology. Microbial Biotechnology 17 (7), e14527 (2024)

Giaveri, S.; Bohra, N.; Diehl, C.; Yang, H. Y.; Ballinger, M.; Paczia, N.; Glatter, T.; Erb, T. J.: Integrated translation and metabolism in a partially self-synthesizing biochemical network. Science 385 (6705), S. 174 - 178 (2024)

Schada v. Borzyskowsi, L.; Lucas, H.; Kremer, K.; Barthel, S.; Pommerenke, B.; Glatter, T.; Paczia, N.; Erhard, B.; Erb, T. J.: Multiple levels of transcriptional regulation control glycolate metabolism in Paracoccus denitrificans. mBio 15 (8), e0152424 (2024)

Burt, M.; Angelidou, G.; Mais, C. N.; Preußer, C.; Glatter, T.; Heimerl, T.; Groß, R.; Serrania, J.; Boosarpu, G.; Pogge von Strandmann, E. et al.; Müller, J. A.; Bange, G.; Becker, A.; Lehmann, M.; Jonigk, D.; Neubert, L.; Freitag, H.; Paczia, N.; Schmeck, B.; Jung, A. L.: Lipid A in outer membrane vesicles shields bacteria from polymyxins. Journal of extracellular vesicles 13 (5), e12447 (2024)

Sendker, F. L.; Lo, Y. K.; Heimerl, T.; Bohn, S.; Persson, L. J.; Mais, C.-N.; Sadowska, W.; Paczia, N.; Nußbaum, E.; del Carmen Sánchez Olmos, M. et al.; Forchhammer, K.; Schindler, D.; Erb, T. J.; Benesch, J. L. P.; Marklund, E. G.; Bange, G.; Schuller, J. M.; Hochberg, G. K. A.: Emergence of fractal geometries in the evolution of a metabolic enzyme. Nature 628 (8009), S. 894 - 900 (2024)

Nomura, S.; Paczia, N.; Kahnt, J.; Shima, S.: Isolation of an H₂-dependent electron-bifurcating CO₂-reducing megacomplex with MvhB polyferredoxin from Methanothermobacter marburgensis. The FEBS Journal 291 (11), S. 2449 - 2460 (2024)

Schaupp, S.; Arriaza-Gallardo, F. J.; Paczia, N.; Ataka, K.; Shima, S.: Acyl and CO ligands in the [Fe]-hydrogenase cofactor scramble upon photolysis. Angewandte Chemie International Edition 63 (6), e202316478 (2024)

Nattermann, M.; Wenk, S.; Pfister, P.; He, H.; Lee, S.H.; Szymanski, W.; Guntermann, N.; Zhu, F.; Nickel, L.; Wallner, C. et al.; Zarzycki, J.; Paczia, N.; Gaißert, N.; Franciò, G.; Leitner, W.; Gonzalez, R.; Erb, T. J.: Engineering a new-to-nature cascade for phosphate-dependent formate to formaldehyde conversion in vitro and in vivo. Nature Communications 14 (1), 2682 (2023)

Gavriil, M.; Proietto, M.; Paczia, N.; Ginolhac, A.; Halder, R.; Valceschini, E.; Sauter, T.; Linster, C. L.; Sinkkonen, L.: 2-Hydroxyglutarate modulates histone methylation at specific loci and alters gene expression via Rph1 inhibition. Life science alliance 7 (2), e202302333 (2023)

Gomes-Filho, J. V.; Breuer, R.; Morales-Filloy, H. G.; Pozhydaieva, N.; Borst, A.; Paczia, N.; Soppa, J.; Höfer, K.; Jäschke, A.; Randau, L.: Identification of NAD-RNA species and ADPR-RNA decapping in Archaea. Nature Communications 14, 7597 (2023)