Publications of Nicole Paczia

Mies, U. S.; Zheng, H.; Meuser, K.; Radek, R.; Paczia, N.; Treitli, S. C.; Brune, A.: Comparative genomics of Elusimicrobiaceae (phylum Elusimicrobiota) and description of the isolates Elusimicrobium simillimum sp. nov., Elusimicrobium posterum sp. nov., and Parelusimicrobium proximum gen. nov. sp. nov. Systematic and Applied Microbiology 48 (3), 126606 (2025)

Pérez-López, M. I.; Lubrano, P.; Angelidou, G.; Hoch, S.; Glatter, T.; Paczia, N.; Link, H.; Sourjik, V.: The SPFH complex HflK-HflC regulates aerobic respiration in bacteria. PLOS Biology 23 (4), e3003077 (2025)

Zheng, L.; Li, W.; Christ, M.; Paczia, N.; Buckel, W.; Mais, C.-N.; Bolker, M.; Freitag, J.; Bange, G.: Mechanistic and structural insights into the itaconate-producing trans-aconitate decarboxylase Tad1. PNAS Nexus 4 (3), pgaf059 (2025)

Orsi, E.; Schulz-Mirbach, H.; Cotton, C. A. R.; Satanowski, A.; Petri, H. M.; Arnold, S. L.; Grabarczyk, N.; Verbakel, R.; Jensen, K. S.; Donati, S. et al.; Paczia, N.; Glatter, T.; Küffner, A. M.; Chotel, T.; Schillmüller, F.; De Maria, A.; He, H.; Lindner, S. N.; Noor, E.; Bar-Even, A.; Erb, T. J.; Nikel, P. I.: Computation-aided designs enable developing auxotrophic metabolic sensors for wide-range glyoxylate and glycolate detection. Nature Communications 16 (1), 2168 (2025)

Schulz-Mirbach, H.; Wichmann, P.; Satanowski, A.; Meusel, H.; Wu, T.; Nattermann, M.; Burgener, S.; Paczia, N.; Bar-Even, A.; Erb, T. J.: New-to-nature CO₂-dependent acetyl-CoA assimilation enabled by an engineered B₁₂-dependent acyl-CoA mutase. Nature Communications 15 (1), 10235 (2024)

Lago-Maciel, A.; Soares, J. C.; Zarzycki, J.; Buchanan, C. J.; Reif-Trauttmansdorff, T.; Schmidt, F. V.; Lometto, S.; Paczia, N.; Schuller, J. M.; Hansen, D. F. et al.; Heller, G. T.; Prinz, S.; Hochberg, G. K. A.; Pierik, A. J.; Rebelein, J. G.: Methylthio-alkane reductases use nitrogenase metalloclusters for carbon-sulfur bond cleavage. bioRxiv: the preprint server for biology, 2024.10.19.619033 (2024)

He, H.; Gómez-Coronado, P. A.; Zarzycki, J.; Barthel, S.; Kahnt, J.; Claus, P.; Klein, M.; Klose, M.; de Crécy-Lagard, V.; Schindler, D. et al.; Paczia, N.; Glatter, T.; Erb, T. J.: Adaptive laboratory evolution recruits the promiscuity of succinate semialdehyde dehydrogenase to repair different metabolic deficiencies. Nature Communications 15 (1), 8898 (2024)

Barthel, S.; Brenker, L.; Diehl, C.; Bohra, N.; Giaveri, S.; Paczia, N.; Erb, T. J.: in vitro transcription-based biosensing of glycolate for prototyping of a complex enzyme cascade. Synthetic Biology, ysae013 (2024)

Pozhydaieva, N.; Billau, F. A.; Wolfram-Schauerte, M.; Ramírez Rojas, A. A.; Paczia, N.; Schindler, D.; Höfer, K.: Temporal epigenome modulation enables efficient bacteriophage engineering and functional analysis of phage DNA modifications. PLOS Genetics 20 (9), e1011384 (2024)

Scarinci, G.; Ariens, J.-L.; Angelidou, G.; Schmidt, S.; Glatter, T.; Paczia, N.; Sourjik, V.: Enhanced metabolic entanglement emerges during the evolution of an interkingdom microbial community. Nature Communications 15 (1), 7238 (2024)

Arias-Rojas, A.; Arifah, A. Q.; Angelidou, G.; Alshaar, B.; Schombel, U.; Forest, E.; Frahm, D.; Brinkmann, V.; Paczia, N.; Beisel, C. L. et al.; Gisch, N.; Iatsenko, I.: MprF-mediated immune evasion is necessary for Lactiplantibacillus plantarum resilience in the Drosophila gut during inflammation. PLOS Pathogens 20 (8), e1012462 (2024)

Schulz-Mirbach, H.; Krüsemann, J. L.; Andreadaki, T.; Nerlich, J. N.; Mavrothalassiti, E.; Boecker, S.; Schneider, P.; Weresow, M.; Abdelwahab, O.; Paczia, N. et al.; Dronsella, B.; Erb, T. J.; Bar-Even, A.; Klamt, S.; Lindner, S. N.: Engineering new-to-nature biochemical conversions by combining fermentative metabolism with respiratory modules. Nature Communications 15 (1), 6725 (2024)

Schann, K.; Bakker, J.; Boinot, M.; Kuschel, P.; He, H.; Nattermann, M.; Paczia, N.; Erb, T. J.; Bar-Even, A.; Wenk, S.: Design, construction and optimization of formaldehyde growth biosensors with broad application in biotechnology. Microbial Biotechnology 17 (7), e14527 (2024)

Giaveri, S.; Bohra, N.; Diehl, C.; Yang, H. Y.; Ballinger, M.; Paczia, N.; Glatter, T.; Erb, T. J.: Integrated translation and metabolism in a partially self-synthesizing biochemical network. Science 385 (6705), pp. 174 - 178 (2024)

Schada v. Borzyskowsi, L.; Lucas, H.; Kremer, K.; Barthel, S.; Pommerenke, B.; Glatter, T.; Paczia, N.; Erhard, B.; Erb, T. J.: Multiple levels of transcriptional regulation control glycolate metabolism in Paracoccus denitrificans. mBio 15 (8), e0152424 (2024)

Burt, M.; Angelidou, G.; Mais, C. N.; Preußer, C.; Glatter, T.; Heimerl, T.; Groß, R.; Serrania, J.; Boosarpu, G.; Pogge von Strandmann, E. et al.; Müller, J. A.; Bange, G.; Becker, A.; Lehmann, M.; Jonigk, D.; Neubert, L.; Freitag, H.; Paczia, N.; Schmeck, B.; Jung, A. L.: Lipid A in outer membrane vesicles shields bacteria from polymyxins. Journal of extracellular vesicles 13 (5), e12447 (2024)

Sendker, F. L.; Lo, Y. K.; Heimerl, T.; Bohn, S.; Persson, L. J.; Mais, C.-N.; Sadowska, W.; Paczia, N.; Nußbaum, E.; del Carmen Sánchez Olmos, M. et al.; Forchhammer, K.; Schindler, D.; Erb, T. J.; Benesch, J. L. P.; Marklund, E. G.; Bange, G.; Schuller, J. M.; Hochberg, G. K. A.: Emergence of fractal geometries in the evolution of a metabolic enzyme. Nature 628 (8009), pp. 894 - 900 (2024)

Nomura, S.; Paczia, N.; Kahnt, J.; Shima, S.: Isolation of an H₂-dependent electron-bifurcating CO₂-reducing megacomplex with MvhB polyferredoxin from Methanothermobacter marburgensis. The FEBS Journal 291 (11), pp. 2449 - 2460 (2024)

Schaupp, S.; Arriaza-Gallardo, F. J.; Paczia, N.; Ataka, K.; Shima, S.: Acyl and CO ligands in the [Fe]-hydrogenase cofactor scramble upon photolysis. Angewandte Chemie International Edition 63 (6), e202316478 (2024)

Nattermann, M.; Wenk, S.; Pfister, P.; He, H.; Lee, S.H.; Szymanski, W.; Guntermann, N.; Zhu, F.; Nickel, L.; Wallner, C. et al.; Zarzycki, J.; Paczia, N.; Gaißert, N.; Franciò, G.; Leitner, W.; Gonzalez, R.; Erb, T. J.: Engineering a new-to-nature cascade for phosphate-dependent formate to formaldehyde conversion in vitro and in vivo. Nature Communications 14 (1), 2682 (2023)