Publications of Jan Zarzycki

Schulz, Luca, Zarzycki, Jan, Steinchen, Wieland, Hochberg, Georg K. A. and Erb, Tobias J.: (2025) Layered entrenchment maintains essentiality in the evolution of Form I Rubisco complexes, The EMBO Journal, Nature Publishing Group, 44, January, pp. 269–280.

Lago-Maciel, Ana, Soares, Jessica C, Zarzycki, Jan, Buchanan, Charles James, Reif-Trauttmansdorff, Tristan, Schmidt, Frederik V., Lometto, Stefano, Paczia, Nicole, Schuller, Jan M, Hansen, D Flemming, Heller, Gabriella T, Prinz, Simone, Hochberg, Georg K. A., Pierik, Antonio J and Rebelein, Johannes G.: (2024) Methylthio-alkane reductases use nitrogenase metalloclusters for carbon-sulfur bond cleavage, bioRxiv: the preprint server for biology, Cold Spring Harbor, NY, Cold Spring Harbor Laboratory, October.

He, Hai, Gómez-Coronado, Paul A., Zarzycki, Jan, Barthel, Sebastian, Kahnt, Jörg, Claus, Peter, Klein, Moritz, Klose, Melanie, de Crécy-Lagard, Valérie, Schindler, Daniel, Paczia, Nicole, Glatter, Timo and Erb, Tobias J.: (2024) Adaptive laboratory evolution recruits the promiscuity of succinate semialdehyde dehydrogenase to repair different metabolic deficiencies, Nature Communications, London, Nature Publishing Group, 15 (1).

Schmidt, Frederik Vincent, Schulz, Luca, Zarzycki, Jan, Prinz, Simone, Oehlmann, Niels Nathan, Erb, Tobias J. and Rebelein, Johannes G.: (2024) Structural insights into the iron nitrogenase complex, Nature Structural & Molecular Biology, New York, NY, Nature Pub. Group, 31 (1), pp. 150–158.

Nattermann, M., Wenk, S., Pfister, Pascal, He, H., Lee, S.H., Szymanski, W., Guntermann, N., Zhu, F., Nickel, L., Wallner, C., Zarzycki, J., Paczia, N., Gaißert, N., Franciò, G., Leitner, W., Gonzalez, R. and Erb, T. J.: (2023) Engineering a new-to-nature cascade for phosphate-dependent formate to formaldehyde conversion in vitro and in vivo, Nature Communications, London, Nature Publishing Group, 14 (1).

Marchal, Daniel G., Schulz, Luca, Schuster, Ingmar, Ivanovska, Jelena, Paczia, Nicole, Prinz, Simone, Zarzycki, Jan and Erb, Tobias J.: (2023) Machine learning-supported enzyme engineering toward improved CO₂-fixation of Glycolyl-CoA carboxylase, ACS Synthetic Biology, Washington, D.C., American Chemical Society, 12 (12), pp. 3521–3530.

Kremer, Katharina, Meier, Doreen, Theis, Lisa, Miller, Stephanie, Rost-Nasshan, Aerin, Naing, Yadanar T., Zarzycki, Jan, Paczia, Nicole, Serrania, Javier, Blumenkamp, Patrick, Goesmann, Alexander, Becker, Anke, Thanbichler, Martin, Hochberg, Georg K. A., Carter, Michael S. and Erb, Tobias J.: (2023) Functional degeneracy in Paracoccus denitrificans Pd1222 is coordinated via RamB, which links expression of the Glyoxylate cycle to activity of the Ethylmalonyl-CoA pathway, Applied and Environmental Microbiology, American Society for Microbiology (ASM), 89 (7).

McLean, Richard, Schwander, Thomas, Diehl, Christoph, Cortina, Nina Socorro, Paczia, Nicole, Zarzycki, Jan and Erb, Tobias J.: (2023) Exploring alternative pathways for the in vitro establishment of the HOPAC cycle for synthetic CO₂ fixation, Science Advances, Washington, AAAS, 9 (24).

Pfister, Pascal, Zarzycki, Jan and Erb, Tobias J.: (2023) Structural basis for a cork-up mechanism of the intra-molecular Mesaconyl-CoA transferase., Biochemistry, Columbus, Ohio, American Chemical Society, 62 (1), pp. 75–84.

Schulz, L., Guo, Z., Zarzycki, J., Steinchen, W., Schuller, J. M., Heimerl, T., Prinz, S., Mueller-Cajar, O., Erb, T. J. and Hochberg, G. K. A.: (2022) Evolution of increased complexity and specificity at the dawn of form I Rubiscos, Science, Washington, D.C., American Association for the Advancement of Science, 378 (6616), pp. 155–160.

Nattermann, M., Burgener, S., Pfister, P., Chou, A., Schulz, L., Lee, S. H., Paczia, Nicole, Zarzycki, J., Gonzalez, R. and Erb, T. J.: (2021) Engineering a highly efficient carboligase for synthetic one-carbon metabolism, ACS Catalysis, Washington, DC, ACS, 11 (9), pp. 5396–5404.

Scheffen, M., Marchal, D. G., Beneyton, T., Schuller, S.K., Klose, M., Diehl, C., Lehmann, J., Pfister, P., Carillo, M., He, H., Aslan, S., Cortina, N. S., Claus, P., Bollschweiler, D., Baret, J.-C., Schuller, J.M., Zarzycki, J., Bar-Even, A. and Erb, T. J.: (2021) A new-to-nature carboxylation module to improve natural and synthetic CO₂ fixation, Nature Catalysis, New York, Nature Publishing Group, 4, pp. 105–115.

Richter, Alexandra A., Kobus, Stefanie, Czech, Laura, Hoeppner, Astrid, Zarzycki, Jan, Erb, Tobias J., Lauterbach, Lukas, Dickschat, Jeroen S., Bremer, Erhard and Smits, Sander H. J.: (2020) The architecture of the diaminobutyrate acetyltransferase active site provides mechanistic insight into the biosynthesis of the chemical chaperone ectoine, JOURNAL OF BIOLOGICAL CHEMISTRY, 295 (9), pp. 2822–2838.

Schada v. Borzyskowsi, Lennart, Severi, Francesca, Krueger, Karen, Hermann, Lucas, Gilardet, Alexandre, Sippel, Felix, Pommerenke, B., Claus, Peter, Cortina, Nina Socorro, Glatter, Timo, Zauner, Stefan, Zarzycki, Jan, Fuchs, Bernhard M., Bremer, Erhard, Maier, Uwe G., Amann I, Rudolf and Erb, Tobias J.: (2019) Marine Proteobacteria metabolize glycolate via the β-hydroxyaspartate cycle, NATURE, 575 (7783), pp. 500-+.

Moog, Daniel, Schmitt, Johanna, Senger, Jana, Zarzycki, Jan, Rexer, Karl-Heinz, Linne, Uwe, Erb, Tobias J. and Maier, Uwe G.: (2019) Using a marine microalga as a chassis for polyethylene terephthalate (PET) degradation, MICROBIAL CELL FACTORIES, 18 (1).

Stoffel, Gabriele M. M., Saez, David Adrian, DeMirci, Hasan, Voegeli, Bastian, Rao, Yashas, Zarzycki, Jan, Yoshikuni, Yasuo, Wakatsuki, Soichi, Vohringer-Martinez, Esteban and Erb, Tobias J.: (2019) Four amino acids define the CO₂ binding pocket of enoyl-CoA carboxylases/reductases, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 116 (28), pp. 13964–13969.

Richer, Alexandra A., Kobus, Stefanie, Czech, Laura, Höppner, Astrid, Zarzycki, Jan, Erb, Tobias J., Lauterbach, Lukas, Dickschat, Jeroen S., Bremer, Erhard and Smits, Sander H. J.: (2019) Making the stress-protectant ectoine: Structural and biochemical insights into the acetyltransferase EctA, Studia Universitatis Babes-Bolyai, Biologia, Cluj-Napoca, Romania, Babeş-Bolyai University, 648 (1), pp. 110–110.

Trudeau, D., Edlich-Muth, C., Zarzycki, J., Scheffen, M., Goldsmith, M., Khersonsky, O., Avizemer, Z., Fleishman, S., Cotton, C., Erb, T. J., Tawfik, D. and Bar-Even, A.: (2018) Design and in vitro realization of carbon-conserving photorespiration, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 115 (49), pp. E11455–E11464.

Berhardsgrütter, I., Vögeli, B., Wagner, T., Peter, D., Cortina, N. S., Kahnt, J., Bange, G., Engilberge, S., Girard, E., Riobe, F., Maury, O., Shima, S., Zarzycki, J. and Erb, T. J.: (2018) The multicatalytic compartment of propionyl-CoA synthase sequesters a toxic metabolite, NATURE CHEMICAL BIOLOGY, 14 (12), p. 1127.

Kerfeld, C., Aussignargues, C., Zarzycki, J., Cai, F. and Sutter, M.: (2018) Bacterial microcompartments, NATURE REVIEWS MICROBIOLOGY, 16 (5), pp. 277–290.