Publications

Pozhydaieva, N.; Höfer, K.: Utilizing Golden Gate Assembly to streamline CRISPR-Cas/NgTET-based phage mutagenesis. In: Golden Gate Cloning. Methods in Molecular Biology, Vol. 2850 , pp. 329 - 343 (Ed. Schindler, D.). Humana, New York, NY. (2025)

Pozhydaieva, N.; Billau, F. A.; Wolfram-Schauerte, M.; Ramírez Rojas, A. A.; Paczia, N.; Schindler, D.; Höfer, K.: Temporal epigenome modulation enables efficient bacteriophage engineering and functional analysis of phage DNA modifications. PLOS Genetics 20 (9), e1011384 (2024)

Yilmaz Demirel, N.; Weber, M.; Höfer, K.: Bridging the gap: RNAylation conjugates RNAs to proteins. Biochimica et Biophysica Acta: BBA 1871 (8), 119826 (2024)

Cortés-Martín, A.; Buttimer, C.; Pozhydaieva, N.; Hille, F.; Shareefdeen, H.; Bolocan, A. S.; Draper, L. A.; Shkoporov , A. N.; Franz , C. M. A. P.; Höfer, K. et al.; Ross, P. R.; Hill, C.: Isolation and characterization of Septuagintavirus; a novel clade of Escherichia coli phages within the subfamily Vequintavirinae. Microbiology Spectrum 12 (9), e00592-24 (2024)

Wolfram-Schauerte, M.; Moskalchuk, A.; Pozhydaieva, N.; Ramírez Rojas, A. A.; Schindler, D.; Kaiser, S.; Paczia, N.; Höfer, K.: T4 phage RNA is NAD-capped and alters the NAD-cap epitranscriptome of Escherichia coli during infection through a phage-encoded decapping enzyme. bioRxiv: the preprint server for biology, 2024.04.04.588121 (2024)

Pozhydaieva, N.; Wolfram-Schauerte, M.; Keuthen, H.; Höfer, K.: The enigmatic epitranscriptome of bacteriophages: putative RNA modifications in viral infections. Current Opinion in Microbiology 77, 102417 (2024)

Gomes-Filho, J. V.; Breuer, R.; Morales-Filloy, H. G.; Pozhydaieva, N.; Borst, A.; Paczia, N.; Soppa, J.; Höfer, K.; Jäschke, A.; Randau, L.: Identification of NAD-RNA species and ADPR-RNA decapping in Archaea. Nature Communications 14, 7597 (2023)

Lai, L. B.; Gopalan, V.; Jansson, M. D.; Chen, Q.; Zhang, X.; Wolfram-Schauerte, M.; Höfer, K.: Making nucleic acid structures and schematics. Trends in Biochemical Sciences 48 (8), pp. 655 - 658 (2023)

Wolfram-Schauerte, M.; Pozhydaieva, N.; Höfer, K.: Molekulare Schnappschüsse der Phageninfektion. (2023)

Gratani, F. L.; Englert, T.; Nashier, P.; Sass, P.; Czech, L.; Neumann, N.; Doello, S.; Mann, P.; Blobelt, R.; Alberti, S. et al.; Forchhammer, K.; Bange, G.; Höfer, K.; Macek, B.: E. coli toxin YjjJ (HipH) is a Ser/Thr protein kinase that impacts cell division, carbon metabolism, and ribosome assembly. mSystems 8 (1), e01043-22 (2023)

Wolfram-Schauerte, M.; Höfer, K.: NAD-capped RNAs - a redox cofactor meets RNA. Trends in Biochemical Sciences 48 (2), pp. 142 - 155 (2023)

Wolfram-Schauerte, M.; Pozhydaieva, N.; Grawenhoff, J.; Welp, L. M.; Silbern, I.; Wulf, A.; Billau, F. A.; Glatter, T.; Urlaub, H.; Jäschke, A. et al.; Höfer, K.: A viral ADP-ribosyltransferase attaches RNA chains to host proteins. Nature 620 (7976), pp. 1054 - 1062 (2023)

Yousefi, M. H.; Wagemans, J.; Shekarforoush, S. S.; Vallino, M.; Pozhydaieva, N.; Höfer, K.; Lavigne, R.; Hosseinzadeh, S.: Isolation and molecular characterization of the Salmonella typhimurium orphan phage Arash. BMC Microbiology 23, 297 (2023)

Wolfram-Schauerte, M.; Pozhydaieva, N.; Viering, M.; Glatter, T.; Höfer, K.: Integrated omics reveal time-resolved insights into T4 phage infection of E. coli on proteome and transcriptome levels. Viruses 14 (11), 2502 (2022)

Hinrichs, R.; Pozhydaieva, N.; Höfer, K.; Graumann, P. L.: Y-complex proteins show RNA-dependent binding events at the cell membrane and distinct single-molecule dynamics. Cells 11 (6), 933 (2022)

Schauerte, M.; Pozhydaieva, N.; Höfer, K.: Shaping the bacterial epitranscriptome-5'-terminal and internal RNA modifications. Advanced Biology 5 (8), e2100834 (2021)

Kolmar, T.; Büllmann, S. M.; Sarter, C.; Höfer, K.; Jäschke, A.: Development of High-Performance Pyrimidine Nucleoside and Oligonucleotide Diarylethene Photoswitches. Angewandte Chemie International Edition 60 (15), pp. 8164 - 8173 (2021)

Kolmar, T.; Bullmann, S. M.; Sarter, C.; Höfer, K.; Jäschke, A.: Development of High-Performance Pyrimidine Nucleoside and Oligonucleotide Diarylethene Photoswitches. Angew Chem Int Ed Engl 60 (15), pp. 8164 - 8173 (2021)

Möhler, M.; Höfer, K.; Jäschke, A.: Synthesis of 5'-Thiamine-Capped RNA. Molecules 25 (23) (2020)

Abele, F.; Höfer, K.; Bernhard, P.; Grawenhoff, J.; Seidel, M.; Krause, A.; Kopf, S.; Schröter, M.; Jäschke, A.: A Novel NAD-RNA Decapping Pathway Discovered by Synthetic Light-Up NAD-RNAs. Biomolecules 10 (4) (2020)

Höfer, K.; Jäschke, A.: Epitranscriptomics: RNA Modifications in Bacteria and Archaea. Microbiol Spectr 6 (3) (2018)

Höfer, K.; Jäschke, A.: NAD-modifizierte RNA: Redox - biochemie trifft RNA-Prozessierung. (2018)

Winz, M. L.; Cahova, H.; Nübel, G.; Frindert, J.; Höfer, K.; Jäschke, A.: Capture and sequencing of NAD-capped RNA sequences with NAD captureSeq. Nat Protoc 12 (1), pp. 122 - 149 (2016)

Höfer, K.; Li, S.; Abele, F.; Frindert, J.; Schlotthauer, J.; Grawenhoff, J.; Du, J.; Patel, D. J.; Jäschke, A.: Structure and function of the bacterial decapping enzyme NudC. Nat Chem Biol 12 (9), pp. 730 - 4 (2016)

Höfer, K.; Jäschke, A.: Molecular biology: A surprise beginning for RNA. Nature 535 (7612), pp. 359 - 60 (2016)

Höfer, K.; Abele, F.; Schlotthauer, J.; Jäschke, A.: Synthesis of 5'-NAD-Capped RNA. Bioconjug Chem 27 (4), pp. 874 - 7 (2016)

Jäschke, A.; Höfer, K.; Nübel, G.; Frindert, J.: Cap-like structures in bacterial RNA and epitranscriptomic modification. Curr Opin Microbiol 30, pp. 44 - 49 (2016)

Cahova, H.; Winz, M. L.; Höfer, K.; Nübel, G.; Jäschke, A.: NAD captureSeq indicates NAD as a bacterial cap for a subset of regulatory RNAs. Nature 519 (7543), pp. 374 - 7 (2015)

Hayden, S. C.; Bryant, J. J.; Mackey, M. A.; Höfer, K.; Lindner, B. D.; Nguyen, V. P.; Jäschke, A.; Bunz, U. H.: Antimicrobial activity of water-soluble triazole phenazine clickamers against E. coli. Chemistry 20 (3), pp. 719 - 23 (2013)

Brameier, M.; Ibing, W.; Höfer, K.; Montag, J.; Stahl-Hennig, C.; Motzkus, D.: Mapping the small RNA content of simian immunodeficiency virions (SIV). PLoS One 8 (9), p. e75063 (2013)

Höfer, K.; Langejürgen, L. V.; Jäschke, A.: Universal aptamer-based real-time monitoring of enzymatic RNA synthesis. J Am Chem Soc 135 (37), pp. 13692 - 4 (2013)