Publications of Helge B. Bode

Cai, X.; Zhao, L.; Bode, H. B.: Engineering of specific single-module nonribosomal peptide synthetases of the RXP type for the production of defined peptides. ACS Synthetic Biology 12 (1), pp. 203 - 212 (2023)

Jin, G.; Hrithik, M. T. H.; Lee, D.-H.; Kim, I.-H.; Jung, J.-S.; Bode, H. B.; Kim, Y.: Manipulation of GameXPeptide synthetase gene expression by a promoter exchange alters the virulence of an entomopathogenic bacterium, Photorhabdus temperata temperata, by modulating insect immune responses. Frontiers in Microbiology 14, 1271764 (2023)

Meesil, W.; Muangpat, P.; Sitthisak, S.; Rattanarojpong, T.; Chantratita, N.; Machado, R. A. R.; Shi, Y.-M.; Bode, H. B.; Vitta, A.; Thanwisai, A.: Genome mining reveals novel biosynthetic gene clusters in entomopathogenic bacteria. Scientific Reports 13, 20764 (2023)

Pandi, A.; Adam, D.; Zare, A.; Trinh, V. T.; Schaefer, S. L.; Burt, M.; Klabunde, B.; Bobkova, E.; Kushwaha, M.; Foroughijabbari, Y. et al.; Braun, P.; Spahn, C. K.; Preußer, C.; Pogge von Strandmann, E.; Bode, H. B.; von Buttlar, H.; Bertrams, W.; Jung, A. L.; Abendroth, F.; Schmeck, B.; Hummer, G.; Vázquez, O.; Erb, T. J.: Cell-free biosynthesis combined with deep learning accelerates de novo-development of antimicrobial peptides. Nature Communications 14 (1), 7197 (2023)

Kavakli, S.; Grammbitter, G. L. C.; Bode, H. B.: Biosynthesis of the multifunctional isopropylstilbene in Photorhabdus laumondii involves cross-talk between specialized and primary metabolism. Tetrahedron 128, 133116 (2022)

Shi, Y.-M.; Crames, J. J.; Czech, L.; Bozhüyük, K. A. J.; Shi, Y.-N.; Hirschmann, M.; Lamberth, S.; Claus, P.; Paczia, N.; Ruckert, C. et al.; Kalinowski, J.; Bange, G.; Bode, H. B.: Genome mining enabled by biosynthetic characterization uncovers a class of benzoxazolinate-containing natural products in diverse bacteria. Angewandte Chemie, International Edition in English 61 (51), e202206106 (2022)

Muangpat, P.; Meesil, W.; Ngoenkam, J.; Teethaisong, Y.; Thummeepak, R.; Sitthisak, S.; Tandhavanant, S.; Chantratita, N.; Bode, H. B.; Vitta, A. et al.; Thanwisai, A.: Genome analysis of secondary metabolitebiosynthetic gene clusters of Photorhabdus akhurstii subsp. akhurstii and its antibacterial activity against antibiotic-resistant bacteria. PLOS ONE 17 (9), e0274956 (2022)

Shi, Y.-M.; Hirschmann, M.; Shi, Y.-N.; Bode, H. B.: Cleavage off-loading and post-assembly-line conversions yield products with unusual termini during biosynthesis. ACS Chemical Biology 17 (8), pp. 2221 - 2228 (2022)

Ahmed, S.; Tafim Hossain Hrithik, M.; Chandra Roy, M.; Bode, H. B.; Kim, Y.: Phurealipids, produced by the entomopathogenic bacteria, Photorhabdus, mimic juvenile hormone to suppress insect immunity and immature development. Journal of Invertebrate Pathology 193, 107799 (2022)

Gulsen, S. H.; Tileklioglu, E.; Bode, E.; Cimen, H.; Ertabaklar, H.; Ulug, D.; Ertug, S.; Wenski, S. L.; Touray, M.; Hazir, C. et al.; Bilecenoglu, D. K.; Yildiz, I.; Bode, H. B.; Hazir, S.: Antiprotozoal activity of different Xenorhabdus and Photorhabdus bacterial secondary metabolites and identification of bioactive compounds using the easyPACId approach. Scientific Reports 12 (1), 10779 (2022)

Abbood, N.; Vo, T. D.; Watzel, J.; Bozhueyuek, K. A. J.; Bode, H. B.: Type S non-ribosomal peptide synthetases for the rapid generation of tailormade peptide libraries. Chemistry – A European Journal 28 (26), e202103963 (2022)

Shi, Y.-M.; Hirschmann, M.; Shi, Y.-N.; Ahmed, S.; Abebew, D.; Tobias, N. J.; Grun, P.; Crames, J. J.; Pöschel, L.; Kuttenlochner, W. et al.; Richter, C.; Herrmann, J.; Muller, R.; Thanwisai, A.; Pidot, S. J.; Stinear, T. P.; Groll, M.; Kim, Y.; Bode, H. B.: Global analysis of biosynthetic gene clusters reveals conserved and unique natural products in entomopathogenic nematode-symbiotic bacteria. Nature Chemistry 14, pp. 701 - 712 (2022)

Sarawi, S.; Shi, Y.-N.; Lotz-Winter, H.; Reschke, K.; Bode, H. B.; Piepenbring, M.: Occurrence and chemotaxonomical analysis of amatoxins in Lepiota spp. (Agaricales). Phytochemistry 195, 113069 (2022)

Abebew, D.; Sayedain, F.; Bode, E.; Bode, H. B.: Uncovering nematicidal natural products from Xenorhabdus bacteria. Journal of Agricultural and Food Chemistry 70 (2), pp. 498 - 506 (2022)

Gerke, J.; Köhler, A. M.; Wennrich, J.-P.; Große, V.; Shao, L.; Heinrich, A. K.; Bode, H. B.; Chen, W.; Surup, F.; Braus, G. H.: Biosynthesis of antibacterial iron-chelating tropolones in Aspergillus nidulans as response to glycopeptide-producing Streptomycetes. Frontiers in Fungal Biology 2, 777474 (2022)

Zolfaghariyan, S.; Shakeri, A.; Asili, J.; Tarighi, S.; Grün, P.; Shi, Y.-M.; Bode, H. B.; Karimi, J.: Cyclic depsipeptides and linear peptides with cytotoxic and antiphytopathogenic activities from symbiotic bacteria of Xenorhabdus (Enterobacteriales: Morganellaceae) genus. Annals of the Entomological Society of America 116 (2), pp. 114 - 124 (2022)

Miethke, M.; Pieroni, M.; Weber, T.; Bronstrup, M.; Hammann, P.; Halby, L.; Arimondo, P. B.; Glaser, P.; Aigle, B.; Bode, H. B. et al.; Moreira, R.; Li, Y.; Luzhetskyy, A.; Medema, M. H.; Pernodet, J.-L.; Stadler, M.; Tormo, J. R.; Genilloud, O.; Truman, A. W.; Weissman, K. J.; Takano, E.; Sabatini, S.; Stegmann, E.; Brotz-Oesterhelt, H.; Wohlleben, W.; Seemann, M.; Empting, M.; Hirsch, A. K. H.; Loretz, B.; Lehr, C.-M.; Titz, A.; Herrmann, J.; Jaeger, T.; Alt, S.; Hesterkamp, T.; Winterhalter, M.; Schiefer, A.; Pfarr, K.; Hoerauf, A.; Graz, H.; Graz, M.; Lindvall, M.; Ramurthy, S.; Karlen, A.; van Dongen, M.; Petkovic, H.; Keller, A.; Peyrane, F.; Donadio, S.; Fraisse, L.; Piddock, L. J. V.; Gilbert, I. H.; Moser, H. E.; Muller, R.: Towards the sustainable discovery and development of new antibiotics. Nature Reviews Chemistry 5 (10), pp. 726 - 749 (2021)

Erkoc, P.; Schmitt, M.; Ingelfinger, R.; Bischoff-Kont, I.; Kopp, L.; Bode, H. B.; Schiffmann, S.; Fuerst, R.: Xenocoumacin 2 reduces protein biosynthesis and inhibits inflammatory and angiogenesis-related processes in endothelial cells. Biomedicine & Pharmacotherapy 140, 111765 (2021)

Cimen, H.; Touray, M.; Gulsen, S. H.; Erincik, O.; Wenski, S. L.; Bode, H. B.; Shapiro-Ilan, D.; Hazir, S.: Antifungal activity of different Xenorhabdus and Photorhabdus species against various fungal phytopathogens and identification of the antifungal compounds from X. szentirmaii. Applied Microbiology and Biotechnology 105 (13), pp. 5517 - 5528 (2021)

Behsaz, B.; Bode, E.; Gurevich, A.; Shi, Y.-N.; Grundmann, F.; Acharya, D.; Caraballo-Rodriguez, A. M.; Bouslimani, A.; Panitchpakdi, M.; Linck, A. et al.; Guan, C.; Oh, J.; Dorrestein, P. C.; Bode, H. B.; Pevzner, P. A.; Mohimani, H.: Integrating genomics and metabolomics for scalable non-ribosomal peptide discovery (vol 12, 3225, 2021). Nature Communications 12 (1), 4318 (2021)